Resistance to multi organ damage after hemorrhagic shock induced ischemia/reperfusion in arctic ground squirrels

Authors

• Lori Bogren
• JM Olson
• J Carpluk
• JT Moore
• KL Drew

Files

Description

•Worldwide hemorrhagic shock is the number one cause of death in trauma patients, the majority of those die from multi organ dysfunction syndrome [1, 2]. •During hemorrhagic shock (HS), the body undergoes global ischemia as blood pressure drops below the threshold at which tissues can be adequately perfused with blood. •Resistance to ischemic injury is a characteristic of hibernating mammals, including ground squirrels. •There is debate on if this resistance is dependant on hibernation season or if it is an intrinsic plasticity of the organism. QUESTION: Are AGS protected from HS‐induced ischemia reperfusion (I/R) injury on the whole organism and tissue–specific levels and if any protection is dependent upon their hibernation season.

Publication Date

4-17-2012

Recommended Citation

Bogren, Lori; Olson, JM; Carpluk, J; Moore, JT; and Drew, KL, "Resistance to multi organ damage after hemorrhagic shock induced ischemia/reperfusion in arctic ground squirrels" (2012). 2012 Research Day Posters. 5.
https://ualaska.researchcommons.org/uaf_ursa_2012_posters/5

Handle

http://hdl.handle.net/11122/1483